What is latest about Stem Cell Research to cure Juvenile Diabetes ? Please help me to know .?
There are 3 suggestions to question “What is latest about Stem Cell Research to cure Juvenile Diabetes ? Please help me to know .?”
Cord blood to treat Type-1 diabetes
A new research, funded by the Juvenile Diabetes Research Foundation and National Institutes of Health, has indicated that umbilical cord blood can help in safely preserving insulin production among children diagnosed with Type-1 diabetes.
The University of Florida researchers studied the feasibility of using a patient’s own cord blood stem cells in reversing the autoimmune properties developing in the pancreas. The cord blood can help restore the ability to make insulin. Cord blood is rich with cells that help regulate the immune system and is often used after treatments for leukaemia or lymphoma.
This is the first attempt at using cord blood as a potential therapy for Type-1 diabetes according to Dr Michael Haller, an assistant professor of medicine and paediatric endocrinologist at University of Florida. The researchers anticipate success in decreasing the immune system’s attack on the pancreas and possible use of stem cells that can differentiate into insulin-producing cells.
Though this study is relatively small in number of patients, the researchers are confident that it is safe. This confidence is based on the metabolic and immunologic changes observed during the study that indicate positive results. The basic strategy behind this option is utilising the "honeymoon period", a period of a few months after diagnosis when the insulin is not required in large quantities. Cord blood infusion during this period can intervene and repair early damage. Researchers warn that thinking of using this research as a single-point approach to treat a complicated disease like Type-1 diabetes may be immature. The treatment will have to be multi-disciplinary, similar to approaches to other disease like AIDS or cancer. Most probably multiple drugs would be required to address the various facets of the disease..
Stem cell and cord blood research offers promise in a variety of areas but at present theoretical benefit is all that we have I am sorry to say. The idea is that with stem cells or cord blood we will be able to ‘instruct’ these cells to become a muscle cell, a nerve cell, and so on. The idea with type 1 diabetes (the term ‘Juvenile Diabetes’ is archaic as type 1 diabetes has been diagnosed in individuals well beyond 40 years of age) is that we may be able to ‘plant’ new beta (insulin producing cells) in the pancreas of the diabetic. The problems are two fold. First we have as yet not been able to replicate beta cells. Second even if we do succeed in replicating beta cells we would not know how to stop the auto-immune response which targeted and destroyed the beta cells in the first place. Immuno-suppressant drugs simply do not work for even when we are able to detect type 1 diabetes before all of the beta cells of the pancreas have been destroyed the destructive process continues despite such immuno-suppressant therapy. Most physicians feel that the news media tends to suggest more hope than they should as most novel approaches to treat disease are theoretical at best and it often takes decades before we are able to determine if these ideas will work or not. The news media thrives on ‘headlines’ so they tend to promote the latest research as tomorrow’s cure. You may be assured that research into ways to interrupt the disease process are on-going and very intense. Pancreatic beta cell transplants have been tried for example and to some degree they seem to work in some people. There is always hope in matters medical and sometimes unexpectant breakthroughs occur. Unfortunately at this time and certainly for a very long time into the future there is nothing to suggest that stem cells or cord blood will ‘cure’ type 1 diabetes. I am sorry. I wish you the very best of health and in all things may God bless.
The stem cell research offers hope in curing diabetes,the reason why lay press is so much interested.Enormous strides have to be made before whole picture is clear which is harmless at the same time.It may take another 20 years or so if at all it is implemented.
Cord blood to treat Type-1 diabetes
A new research, funded by the Juvenile Diabetes Research Foundation and National Institutes of Health, has indicated that umbilical cord blood can help in safely preserving insulin production among children diagnosed with Type-1 diabetes.
The University of Florida researchers studied the feasibility of using a patient’s own cord blood stem cells in reversing the autoimmune properties developing in the pancreas. The cord blood can help restore the ability to make insulin. Cord blood is rich with cells that help regulate the immune system and is often used after treatments for leukaemia or lymphoma.
This is the first attempt at using cord blood as a potential therapy for Type-1 diabetes according to Dr Michael Haller, an assistant professor of medicine and paediatric endocrinologist at University of Florida. The researchers anticipate success in decreasing the immune system’s attack on the pancreas and possible use of stem cells that can differentiate into insulin-producing cells.
Though this study is relatively small in number of patients, the researchers are confident that it is safe. This confidence is based on the metabolic and immunologic changes observed during the study that indicate positive results. The basic strategy behind this option is utilising the "honeymoon period", a period of a few months after diagnosis when the insulin is not required in large quantities. Cord blood infusion during this period can intervene and repair early damage. Researchers warn that thinking of using this research as a single-point approach to treat a complicated disease like Type-1 diabetes may be immature. The treatment will have to be multi-disciplinary, similar to approaches to other disease like AIDS or cancer. Most probably multiple drugs would be required to address the various facets of the disease..
http://completewellbeing.com/article/understanding-diabetes-in-the-youth/
Stem cell and cord blood research offers promise in a variety of areas but at present theoretical benefit is all that we have I am sorry to say. The idea is that with stem cells or cord blood we will be able to ‘instruct’ these cells to become a muscle cell, a nerve cell, and so on. The idea with type 1 diabetes (the term ‘Juvenile Diabetes’ is archaic as type 1 diabetes has been diagnosed in individuals well beyond 40 years of age) is that we may be able to ‘plant’ new beta (insulin producing cells) in the pancreas of the diabetic. The problems are two fold. First we have as yet not been able to replicate beta cells. Second even if we do succeed in replicating beta cells we would not know how to stop the auto-immune response which targeted and destroyed the beta cells in the first place. Immuno-suppressant drugs simply do not work for even when we are able to detect type 1 diabetes before all of the beta cells of the pancreas have been destroyed the destructive process continues despite such immuno-suppressant therapy. Most physicians feel that the news media tends to suggest more hope than they should as most novel approaches to treat disease are theoretical at best and it often takes decades before we are able to determine if these ideas will work or not. The news media thrives on ‘headlines’ so they tend to promote the latest research as tomorrow’s cure. You may be assured that research into ways to interrupt the disease process are on-going and very intense. Pancreatic beta cell transplants have been tried for example and to some degree they seem to work in some people. There is always hope in matters medical and sometimes unexpectant breakthroughs occur. Unfortunately at this time and certainly for a very long time into the future there is nothing to suggest that stem cells or cord blood will ‘cure’ type 1 diabetes. I am sorry. I wish you the very best of health and in all things may God bless.
The stem cell research offers hope in curing diabetes,the reason why lay press is so much interested.Enormous strides have to be made before whole picture is clear which is harmless at the same time.It may take another 20 years or so if at all it is implemented.